Jumbo Bacteriophages: An Overview

Jumbo Bacteriophages: An Overview

Tailed bacteriophages with genomes larger than 200 kbp are classified as Jumbo phages, and are rarely isolated by conventional methods. These phages are designated "jumbo" owing to their most notable features of a large phage virion and large genome size. However, in addition to these, jumbo phages also exhibit several novel characteristics that have not been observed for phages with smaller ge...

Capsids and Genomes of Jumbo-Sized Bacteriophages Reveal the Evolutionary Reach of the HK97 Fold

Large icosahedral viruses that infect bacteria represent an extreme of the coevolution of capsids and the genomes they accommodate. One subset of these large viruses is the jumbophages, tailed phages with double-stranded DNA genomes of at least 200,000 bp. We explored the mechanism leading to increased capsid and genome sizes by characterizing structures of several jumbophage capsids and the DN...

An Overview of Candiduria

Candida microorganisms frequently exist as saprophytes on the external genitalia or urethra, however, yeast in measurable quantities are found in <1% of clean voided urine specimens. The overall frequency of Candida infections in hospitals has increased by 200% to 300% in the last decade, such that in a general hospital 5% of urine cultures may yield Candida species, and in tertiary-care center...

An Overview on Tuberculosis

بیماری سل یک عفونت باکتریایی مزمن است که توسط مایکوباکتریوم توبرکلوزیس ایجاد شده و توسط تشکیل گرانولوما در بافتهای آلوده مشخص می گردد. شایعترین مکان بروز بیماری، ریه ها می باشند. هر چند که سایر ارگانها نیز ممکن است، درگیر بیماری شوند. سل یک بیماری جدید و ناشناخته نیست. این بیماری در گذشته به عنوان کشنده شماره یک در ایالات متحده محسوب می شد و اکنون نیز به عنوان یک عامل مهم مرگ در کل جهان مطرح است.

Human brucellosis: An overview